Advanced Regenerative Skincare Backed by Science

At the core of our innovation is a proprietary biotechnology process that harnesses the regenerative power of HUMSC. Using advanced cultivation and purification techniques, we extract a high-purity conditioned media rich in cytokines, growth factors, and exosomes—delivering exceptional cellular skin renewal.

This scientifically driven formula is designed to repair, rejuvenate, and restore skin vitality, offering visibly transformative results for aging, stressed, or damaged skin.

Key Regenerative Components

• HGF (Hepatocyte Growth Factor)
  Stimulates skin cell proliferation and enhances blood vessel formation for healthier, more resilient tissue.
• PDGF (Platelet-Derived Growth Factor)
  Supports the regeneration of fibroblasts and endothelial cells, improving skin elasticity, firmness, and smoothness.
• IGF (Insulin-Like Growth Factor)
  Promotes cellular renewal and collagen production, reducing the appearance of fine lines and sagging skin.
• bFGF (Basic Fibroblast Growth Factor)
  Stimulates dermal cell proliferation and collagen remodeling, resulting in firmer, plumper skin.
• aFGF (Acidic Fibroblast Growth Factor)
  Accelerates skin repair and regeneration, enhancing texture and radiance.
• EGF (Epidermal Growth Factor)
  Enhances epidermal turnover to diminish dullness, fine lines, and pigmentation, revealing a smoother, clearer complexion.
• TSP-2 (Thrombospondin-2)
  Reinforces the skin’s structural foundation by supporting collagen fiber formation within the extracellular matrix.
• MCP-1 (Monocyte Chemoattractant Protein-1)
  Helps clear out aged or pigmented cells, visibly brightening the complexion and reducing uneven skin tone.
• TGF-β (Transforming Growth Factor-beta)
  Boosts collagen and elastin synthesis, improves hydration, and provides potent anti-inflammatory benefits for damaged skin.
• TGF-α (Transforming Growth Factor-alpha)
  Activates keratinocyte regeneration, speeding up cell turnover and aiding in recovery from environmental stressors.
• IFN-γ (Interferon-gamma)
  Evens out skin tone and minimizes pigmentation, restoring clarity and luminosity.
• CD9 / CD63 (Exosome Markers)
  Essential proteins that promote the deep delivery of regenerative signals, amplifying collagen synthesis and skin renewal.

How These Regenerative Components Work

The Power of Paracrine Signaling in Skin Renewal
Paracrine signaling is the biological process by which cells communicate with neighboring cells via the release of bioactive molecules—such as exosomes, cytokines, and growth factors. These messengers stimulate nearby cells to initiate tissue repair and regeneration. This process underpins the remarkable effectiveness of our HUMSC-conditioned media, ensuring that regenerative signals are delivered exactly where they’re needed.

The HUMSC Advantage

HUMSC represent some of the most potent cells available, offering unmatched levels of regenerative signaling. Compared to other mesenchymal stem cell sources, HUMSC produce significantly higher concentrations of:

• Growth factors
• Cytokines
• Exosomes

These crucial components deliver multiple skin benefits, including:

• Enhanced collagen and elastin production
• Accelerated cellular turnover
• Improved texture, elasticity, and resilience
• Optimized natural repair mechanisms

Thanks to this powerful paracrine effect, HUMSC-conditioned media consistently demonstrates superior results in anti-aging, aesthetic treatments, and overall regenerative skincare.

Recommended Clinical Applications

1. Post-Treatment Enhancement
   Apply our HUMSC-conditioned media immediately following microneedling, fractional laser, or other aesthetic treatments to accelerate healing, minimize downtime, and amplify results.
2. At-Home Maintenance
   Incorporate this medical-grade formulation into your daily skincare routine to maintain and extend clinic-level benefits, ensuring long-term rejuvenation and skin health.